a detailed analysis (Baumann et al., 1995) of the guarana ́ fruit (P. cupana H.B.K. var. sorbilis (Mart.) Ducke), the caffeine-rich seeds of which are traditionally used by the natives in the central Amazon region of Brazil to prepare a stimulating beverage (Henman, 1982). The concern of the present study, however, is to investigate the liana Paullinia yoco, a caffeine-containing plant of which only the bark serves for the preparation of a stimulant (Schultes, 1987). The traditional and geographically very restricted use by the Indians consists of rasping the stem cortex and either squeezing or simply immersing the resulting mass into cold water to prepare a caffeine-rich drink.